Vaccination Safety by Dr. Nawal AlKaabi
The passive surveillance system, relying primarily on spontaneous reports from health workers, indicated at least a fourfold increase over the expected number of intussusception cases.
As a result, additional studies were conducted better to understand the relationship between the rotavirus vaccine and intussusception. In light of these studies, the rotavirus vaccine manufacturer voluntarily removed its product from the market less than a year after it had been introduced, and the recommendation for routine use of the rotavirus vaccine among infants in the USA was withdrawn.